Polynucleotide Treatment

Regenerate, restore, & strengthen your skin from within

Polynucleotide therapy is a cutting-edge regenerative skin treatment that uses naturally derived molecules to support healing, hydration, and tissue repair. Unlike fillers or skinboosters, polynucleotides work on a cellular level to stimulate collagen production, reduce inflammation, and improve the skin’s long-term resilience.

At Gentle Facial Aesthetics, we offer polynucleotide treatments to clients seeking a science-backed solution for tired, stressed, or ageing skin. Known for their ability to enhance skin health over time, these treatments are especially suitable for sensitive or compromised skin types.

What Is Polynucleotide Therapy?

Polynucleotides are biocompatible molecules that act as powerful messengers for skin regeneration. When injected into the skin, they encourage fibroblast activity (the cells responsible for collagen production), neutralise free radicals, and reduce inflammation.

Polynucleotide therapy works differently from other hydration or rejuvenation treatments:

  • It regenerates rather than fills or lifts
  • It’s suitable for reactive or sensitive skin
  • It delivers progressive, natural improvement over time

Benefits of Polynucleotide Treatment

Polynucleotide injections

Polynucleotide injections help strengthen skin structure from within, with benefits including:

  • Improved hydration and elasticity
  • Reduction in fine lines and crepiness
  • Enhanced skin barrier and texture
  • Soothing effect on inflamed or acne-prone skin
  • Support for healing post-laser or aesthetic treatments

Who Is It For?

  • This treatment is ideal for clients who:
  • Struggle with skin sensitivity or inflammation
  • Experience early signs of skin ageing
  • Have dull, dehydrated, or tired-looking skin
  • Are recovering from aesthetic or skin procedures
  • Want a regenerative option with long-term skin benefits

The Polynucleotide Process

As with all our treatments, your journey begins with a detailed consultation. Once suitability is confirmed, we design a personalised plan based on your skin’s needs and schedule your appointment.

During treatment:

  • Injections are placed into targeted areas of concern (e.g., face, under-eyes, neck)
  • Numbing cream is applied for comfort
  • The process takes around 20–30 minutes
  • A course of 2–3 treatments is typically recommended for optimal results
  • You may experience slight redness or small bumps at the injection points – these usually settle within 24–48 hours.

Before & After

Your Consultation

Our 30-minute consultation allows us to assess your skin, understand your goals, and ensure polynucleotides are the right fit for you. We offer both in-person and video consultations.

FAQs

> Yes – polynucleotides are known for their anti-inflammatory and soothing properties, making them ideal for sensitive, reactive, or damaged skin.

> Results develop gradually. Many clients notice an improvement in skin tone, elasticity, and comfort within a few weeks.

> Absolutely. It’s often used alongside skinboosters, facials, or energy-based devices for enhanced skin health.

> A course of 2–3 treatments is typically recommended, followed by maintenance every 4–6 months depending on your goals.

> Minimal. You may experience slight redness or raised areas at the injection sites, which usually subside within a day or two.

Need More Information?

You can get in touch via our or call us directly on with any questions before booking.